12 Games
| G | Date | Day | School | Opponent | Conf | Pts | Opp | W | L | Streak | Notes | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 2, 2010 | Thu | Central Michigan | Hampton | Non-Major | W | 33 | 0 | 1 | 0 | W 1 | ||
| 2 | Sep 9, 2010 | Thu | Central Michigan | @ | Temple | MAC | L | 10 | 13 | 1 | 1 | L 1 | |
| 3 | Sep 18, 2010 | Sat | Central Michigan | @ | Eastern Michigan | MAC | W | 52 | 14 | 2 | 1 | W 1 | |
| 4 | Sep 25, 2010 | Sat | Central Michigan | @ | Northwestern | Big Ten | L | 25 | 30 | 2 | 2 | L 1 | |
| 5 | Oct 2, 2010 | Sat | Central Michigan | Ball State | MAC | L | 17 | 31 | 2 | 3 | L 2 | ||
| 6 | Oct 9, 2010 | Sat | Central Michigan | @ | Virginia Tech | ACC | L | 21 | 45 | 2 | 4 | L 3 | |
| 7 | Oct 16, 2010 | Sat | Central Michigan | Miami (OH) | MAC | L | 20 | 27 | 2 | 5 | L 4 | ||
| 8 | Oct 23, 2010 | Sat | Central Michigan | @ | Northern Illinois | MAC | L | 7 | 33 | 2 | 6 | L 5 | |
| 9 | Oct 30, 2010 | Sat | Central Michigan | Bowling Green | MAC | L | 14 | 17 | 2 | 7 | L 6 | ||
| 10 | Nov 5, 2010 | Fri | Central Michigan | Western Michigan | MAC | W | 26 | 22 | 3 | 7 | W 1 | ||
| 11 | Nov 13, 2010 | Sat | Central Michigan | @ | Navy | Ind | L | 37 | 38 | 3 | 8 | L 1 | |
| 12 | Nov 26, 2010 | Fri | Central Michigan | @ | Toledo | MAC | L | 31 | 42 | 3 | 9 | L 2 |
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