| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | 1 | 2015-09-05 | Clemson | Wofford | REG (Non-Conf) | W 49-10 | ||
| 2 | 2 | 2 | 2015-09-12 | Clemson | Appalachian State | REG (Non-Conf) | W 41-10 | ||
| 3 | 3 | 4 | 2015-10-03 | Clemson | Notre Dame | REG (Non-Conf) | W 24-22 | ||
| 4 | 4 | 5 | 2015-10-10 | Clemson | Georgia Tech | REG (Conf) | W 43-24 | ||
| 5 | 5 | 6 | 2015-10-17 | Clemson | Boston College | REG (Conf) | W 34-17 | ||
| 6 | 6 | 7 | 2015-10-24 | Clemson | @ | Miami (FL) | REG (Conf) | W 58-0 | |
| 7 | 7 | 9 | 2015-11-07 | Clemson | Florida State | REG (Conf) | W 23-13 | ||
| 8 | 8 | 10 | 2015-11-14 | Clemson | @ | Syracuse | REG (Conf) | W 37-27 | |
| 9 | 9 | 11 | 2015-11-21 | Clemson | Wake Forest | REG (Conf) | W 33-13 | ||
| 10 | 10 | 12 | 2015-11-28 | Clemson | @ | South Carolina | REG (Non-Conf) | W 37-32 | |
| 11 | 11 | 13 | 2015-12-05 | Clemson | N | North Carolina | Conf Championship | W 45-37 | |
| 12 | 12 | 14 | 2015-12-31 | Clemson | N | Oklahoma | CFB Semifinal | W 37-17 | Orange Bowl |
| 13 | 13 | 15 | 2016-01-11 | Clemson | N | Alabama | CFB Championship | L 40-45 | College Football Playoff National Championship |
| 12-1 |
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