46 Games
- Conference games only
- Click date for box score, if available
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 10, 2022 | 6:00 PM | Sat | Kansas | 55 | @ | West Virginia | 42 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 2 | Sep 24, 2022 | 12:00 PM | Sat | (17) Baylor | 31 | @ | Iowa State | 24 | |
| 3 | Sep 24, 2022 | 8:00 PM | Sat | Kansas State | 41 | @ | (6) Oklahoma | 34 | |
| 4 | Sep 24, 2022 | 3:30 PM | Sat | Texas Tech | 37 | (22) Texas | 34 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 5 | Oct 1, 2022 | 3:30 PM | Sat | Kansas | 14 | Iowa State | 11 | ||
| 6 | Oct 1, 2022 | 12:00 PM | Sat | (25) Kansas State | 37 | Texas Tech | 28 | ||
| 7 | Oct 1, 2022 | 3:30 PM | Sat | (9) Oklahoma State | 36 | @ | (16) Baylor | 25 | |
| 8 | Oct 1, 2022 | 7:30 PM | Sat | Texas | 38 | West Virginia | 20 | ||
| 9 | Oct 1, 2022 | 12:00 PM | Sat | Texas Christian | 55 | (18) Oklahoma | 24 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 10 | Oct 8, 2022 | 7:30 PM | Sat | (20) Kansas State | 10 | @ | Iowa State | 9 | |
| 11 | Oct 8, 2022 | 3:30 PM | Sat | (7) Oklahoma State | 41 | Texas Tech | 31 | ||
| 12 | Oct 8, 2022 | 12:00 PM | Sat | Texas | 49 | N | Oklahoma | 0 | |
| 13 | Oct 8, 2022 | 12:00 PM | Sat | (17) Texas Christian | 38 | @ | (19) Kansas | 31 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 14 | Oct 13, 2022 | 7:00 PM | Thu | West Virginia | 43 | Baylor | 40 | ||
| 15 | Oct 15, 2022 | 12:00 PM | Sat | Oklahoma | 52 | (19) Kansas | 42 | ||
| 16 | Oct 15, 2022 | 12:00 PM | Sat | (22) Texas | 24 | Iowa State | 21 | ||
| 17 | Oct 15, 2022 | 3:30 PM | Sat | (13) Texas Christian | 43 | (8) Oklahoma State | 40 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 18 | Oct 22, 2022 | 12:00 PM | Sat | Baylor | 35 | Kansas | 23 | ||
| 19 | Oct 22, 2022 | 3:30 PM | Sat | (11) Oklahoma State | 41 | (20) Texas | 34 | ||
| 20 | Oct 22, 2022 | 8:00 PM | Sat | (8) Texas Christian | 38 | (17) Kansas State | 28 | ||
| 21 | Oct 22, 2022 | 3:00 PM | Sat | Texas Tech | 48 | West Virginia | 10 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 22 | Oct 29, 2022 | 7:30 PM | Sat | Baylor | 45 | @ | Texas Tech | 17 | |
| 23 | Oct 29, 2022 | 3:30 PM | Sat | (22) Kansas State | 48 | (9) Oklahoma State | 0 | ||
| 24 | Oct 29, 2022 | 12:00 PM | Sat | Oklahoma | 27 | @ | Iowa State | 13 | |
| 25 | Oct 29, 2022 | 12:00 PM | Sat | (7) Texas Christian | 41 | @ | West Virginia | 31 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 26 | Nov 5, 2022 | 3:00 PM | Sat | Baylor | 38 | @ | Oklahoma | 35 | |
| 27 | Nov 5, 2022 | 3:30 PM | Sat | Iowa State | 31 | West Virginia | 14 | ||
| 28 | Nov 5, 2022 | 3:30 PM | Sat | Kansas | 37 | (18) Oklahoma State | 16 | ||
| 29 | Nov 5, 2022 | 7:00 PM | Sat | Texas | 34 | @ | (13) Kansas State | 27 | |
| 30 | Nov 5, 2022 | 12:00 PM | Sat | (7) Texas Christian | 34 | Texas Tech | 24 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 31 | Nov 12, 2022 | 7:00 PM | Sat | (23) Kansas State | 31 | @ | Baylor | 3 | |
| 32 | Nov 12, 2022 | 3:30 PM | Sat | Oklahoma State | 20 | Iowa State | 14 | ||
| 33 | Nov 12, 2022 | 7:30 PM | Sat | (4) Texas Christian | 17 | @ | (18) Texas | 10 | |
| 34 | Nov 12, 2022 | 7:00 PM | Sat | Texas Tech | 43 | Kansas | 28 | ||
| 35 | Nov 12, 2022 | 12:00 PM | Sat | West Virginia | 23 | Oklahoma | 20 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 36 | Nov 19, 2022 | 2:00 PM | Sat | (19) Kansas State | 48 | @ | West Virginia | 31 | |
| 37 | Nov 19, 2022 | 7:30 PM | Sat | Oklahoma | 28 | (24) Oklahoma State | 13 | ||
| 38 | Nov 19, 2022 | 3:30 PM | Sat | Texas | 55 | @ | Kansas | 14 | |
| 39 | Nov 19, 2022 | 12:00 PM | Sat | (4) Texas Christian | 29 | @ | Baylor | 28 | |
| 40 | Nov 19, 2022 | 7:00 PM | Sat | Texas Tech | 14 | @ | Iowa State | 10 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 41 | Nov 25, 2022 | 1:00 PM | Fri | (24) Texas | 38 | Baylor | 27 | ||
| 42 | Nov 26, 2022 | 8:00 PM | Sat | (15) Kansas State | 47 | Kansas | 27 | ||
| 43 | Nov 26, 2022 | 4:00 PM | Sat | (4) Texas Christian | 62 | Iowa State | 14 | ||
| 44 | Nov 26, 2022 | 7:30 PM | Sat | Texas Tech | 51 | Oklahoma | 48 | ||
| 45 | Nov 26, 2022 | 12:00 PM | Sat | West Virginia | 24 | @ | Oklahoma State | 19 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 46 | Dec 3, 2022 | 12:00 PM | Sat | (13) Kansas State | 31 | N | (3) Texas Christian | 28 |
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