45 Games
- Conference games only
- Click date for box score, if available
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 26, 2015 | 3:30 PM | Sat | (24) Oklahoma State | 30 | @ | Texas | 27 | |
| 2 | Sep 26, 2015 | 4:45 PM | Sat | (3) Texas Christian | 55 | @ | Texas Tech | 52 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 3 | Oct 3, 2015 | 3:30 PM | Sat | (5) Baylor | 63 | N | Texas Tech | 35 | AT&T Stadium - Arlington Texas |
| 4 | Oct 3, 2015 | 12:00 PM | Sat | Iowa State | 38 | Kansas | 13 | ||
| 5 | Oct 3, 2015 | 12:00 PM | Sat | (15) Oklahoma | 44 | (23) West Virginia | 24 | ||
| 6 | Oct 3, 2015 | 4:00 PM | Sat | (20) Oklahoma State | 36 | Kansas State | 34 | ||
| 7 | Oct 3, 2015 | 12:00 PM | Sat | (4) Texas Christian | 50 | Texas | 7 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 8 | Oct 10, 2015 | 12:00 PM | Sat | (3) Baylor | 66 | @ | Kansas | 7 | |
| 9 | Oct 10, 2015 | 7:00 PM | Sat | (21) Oklahoma State | 33 | @ | West Virginia | 26 | |
| 10 | Oct 10, 2015 | 12:00 PM | Sat | Texas | 24 | N | (10) Oklahoma | 17 | Cotton Bowl Stadium - Dallas Texas |
| 11 | Oct 10, 2015 | 7:30 PM | Sat | (2) Texas Christian | 52 | @ | Kansas State | 45 | |
| 12 | Oct 10, 2015 | 3:30 PM | Sat | Texas Tech | 66 | Iowa State | 31 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 13 | Oct 17, 2015 | 12:00 PM | Sat | (2) Baylor | 62 | West Virginia | 38 | ||
| 14 | Oct 17, 2015 | 3:30 PM | Sat | (19) Oklahoma | 55 | @ | Kansas State | 0 | |
| 15 | Oct 17, 2015 | 7:00 PM | Sat | (3) Texas Christian | 45 | @ | Iowa State | 21 | |
| 16 | Oct 17, 2015 | 12:00 PM | Sat | Texas Tech | 30 | @ | Kansas | 20 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 17 | Oct 24, 2015 | 12:00 PM | Sat | (2) Baylor | 45 | Iowa State | 27 | ||
| 18 | Oct 24, 2015 | 3:30 PM | Sat | (17) Oklahoma | 63 | Texas Tech | 27 | ||
| 19 | Oct 24, 2015 | 3:30 PM | Sat | (14) Oklahoma State | 58 | Kansas | 10 | ||
| 20 | Oct 24, 2015 | 12:00 PM | Sat | Texas | 23 | Kansas State | 9 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 21 | Oct 29, 2015 | 7:30 PM | Thu | (5) Texas Christian | 40 | West Virginia | 10 | ||
| 22 | Oct 31, 2015 | 7:00 PM | Sat | Iowa State | 24 | Texas | 0 | ||
| 23 | Oct 31, 2015 | 3:30 PM | Sat | (14) Oklahoma | 62 | @ | Kansas | 7 | |
| 24 | Oct 31, 2015 | 3:30 PM | Sat | (12) Oklahoma State | 70 | @ | Texas Tech | 53 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 25 | Nov 5, 2015 | 7:30 PM | Thu | (2) Baylor | 31 | @ | Kansas State | 24 | |
| 26 | Nov 7, 2015 | 7:00 PM | Sat | (14) Oklahoma | 52 | Iowa State | 16 | ||
| 27 | Nov 7, 2015 | 3:30 PM | Sat | (12) Oklahoma State | 49 | (5) Texas Christian | 29 | ||
| 28 | Nov 7, 2015 | 8:00 PM | Sat | Texas | 59 | Kansas | 20 | ||
| 29 | Nov 7, 2015 | 12:00 PM | Sat | West Virginia | 31 | Texas Tech | 26 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 30 | Nov 14, 2015 | 8:00 PM | Sat | (12) Oklahoma | 44 | @ | (4) Baylor | 34 | |
| 31 | Nov 14, 2015 | 3:30 PM | Sat | (5) Oklahoma State | 35 | @ | Iowa State | 31 | |
| 32 | Nov 14, 2015 | 12:00 PM | Sat | (13) Texas Christian | 23 | Kansas | 17 | ||
| 33 | Nov 14, 2015 | 3:30 PM | Sat | Texas Tech | 59 | Kansas State | 44 | ||
| 34 | Nov 14, 2015 | 12:00 PM | Sat | West Virginia | 38 | Texas | 20 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 35 | Nov 21, 2015 | 7:30 PM | Sat | (10) Baylor | 45 | @ | (4) Oklahoma State | 35 | |
| 36 | Nov 21, 2015 | 12:00 PM | Sat | Kansas State | 38 | Iowa State | 35 | ||
| 37 | Nov 21, 2015 | 8:00 PM | Sat | (7) Oklahoma | 30 | (11) Texas Christian | 29 | ||
| 38 | Nov 21, 2015 | 12:00 PM | Sat | West Virginia | 49 | @ | Kansas | 0 | |
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 39 | Nov 26, 2015 | 7:30 PM | Thu | Texas Tech | 48 | @ | Texas | 45 | |
| 40 | Nov 27, 2015 | 7:30 PM | Fri | (15) Texas Christian | 28 | (7) Baylor | 21 | ||
| 41 | Nov 28, 2015 | 4:00 PM | Sat | Kansas State | 45 | @ | Kansas | 14 | |
| 42 | Nov 28, 2015 | 8:00 PM | Sat | (5) Oklahoma | 58 | @ | (9) Oklahoma State | 23 | |
| 43 | Nov 28, 2015 | 12:00 PM | Sat | West Virginia | 30 | Iowa State | 6 | ||
| Rk | Date | Time | Day | Winner | Pts | Loser | Pts | Notes | |
| 44 | Dec 5, 2015 | 4:30 PM | Sat | Kansas State | 24 | West Virginia | 23 | ||
| 45 | Dec 5, 2015 | 12:00 PM | Sat | Texas | 23 | @ | (12) Baylor | 17 |
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