Output includes regular season games from 2000 to 2024 and bowl games from 2002 to 2024.
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | |
|---|---|---|---|---|---|---|---|---|
| 1 | 1 | 2 | 2021-09-11 | Massachusetts | Boston College | REG (Non-Conf) | L 28-45 | |
| 2 | 2 | 3 | 2021-09-18 | Massachusetts | Eastern Michigan | REG (Non-Conf) | L 28-42 | |
| 3 | 3 | 4 | 2021-09-25 | Massachusetts | @ | Coastal Carolina | REG (Non-Conf) | L 3-53 |
| 4 | 4 | 5 | 2021-10-02 | Massachusetts | Toledo | REG (Non-Conf) | L 7-45 | |
| 5 | 5 | 6 | 2021-10-09 | Massachusetts | Connecticut | REG (Non-Conf) | W 27-13 | |
| 6 | 6 | 7 | 2021-10-23 | Massachusetts | @ | Florida State | REG (Non-Conf) | L 3-59 |
| 7 | 7 | 8 | 2021-10-30 | Massachusetts | @ | Liberty | REG (Non-Conf) | L 17-62 |
| 8 | 8 | 9 | 2021-11-06 | Massachusetts | Rhode Island | REG (Non-Conf) | L 22-35 | |
| 1-7 |
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