| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 4 | 1 | 2022-09-01 | Wake Forest | VMI | REG (Non-Conf) | W 44-10 | ||
| 2 | 5 | 2 | 2022-09-10 | Wake Forest | @ | Vanderbilt | REG (Non-Conf) | W 45-25 | |
| 3 | 6 | 3 | 2022-09-17 | Wake Forest | Liberty | REG (Non-Conf) | W 37-36 | ||
| 4 | 7 | 4 | 2022-09-24 | Wake Forest | Clemson | REG (Conf) | L 45-51 (2OT) | ||
| 5 | 8 | 5 | 2022-10-01 | Wake Forest | @ | Florida State | REG (Conf) | W 31-21 | |
| 6 | 9 | 6 | 2022-10-08 | Wake Forest | Army | REG (Non-Conf) | W 45-10 | ||
| 7 | 10 | 7 | 2022-10-22 | Wake Forest | Boston College | REG (Conf) | W 43-15 | ||
| 8 | 11 | 8 | 2022-10-29 | Wake Forest | @ | Louisville | REG (Conf) | L 21-48 | |
| 9 | 12 | 9 | 2022-11-05 | Wake Forest | @ | North Carolina State | REG (Conf) | L 21-30 | |
| 10 | 13 | 10 | 2022-11-12 | Wake Forest | North Carolina | REG (Conf) | L 34-36 | ||
| 11 | 14 | 11 | 2022-11-19 | Wake Forest | Syracuse | REG (Conf) | W 45-35 | ||
| 12 | 15 | 12 | 2022-11-26 | Wake Forest | @ | Duke | REG (Conf) | L 31-34 | |
| 13 | 16 | 13 | 2022-12-23 | Wake Forest | N | Missouri | Bowl | W 27-17 | Gasparilla Bowl |
| 8-5 |
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