Output includes regular season games from 2000 to 2024 and bowl games from 2002 to 2024.
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | 1 | 2018-09-01 | Clemson | Furman | REG (Non-Conf) | W 48-7 | ||
| 2 | 2 | 3 | 2018-09-15 | Clemson | Georgia Southern | REG (Non-Conf) | W 38-7 | ||
| 3 | 3 | 4 | 2018-09-22 | Clemson | @ | Georgia Tech | REG (Conf) | W 49-21 | |
| 4 | 4 | 5 | 2018-09-29 | Clemson | Syracuse | REG (Conf) | W 27-23 | ||
| 5 | 5 | 6 | 2018-10-06 | Clemson | @ | Wake Forest | REG (Conf) | W 63-3 | |
| 6 | 6 | 7 | 2018-10-20 | Clemson | North Carolina State | REG (Conf) | W 41-7 | ||
| 7 | 7 | 8 | 2018-10-27 | Clemson | @ | Florida State | REG (Conf) | W 59-10 | |
| 8 | 8 | 10 | 2018-11-10 | Clemson | @ | Boston College | REG (Conf) | W 27-7 | |
| 9 | 9 | 11 | 2018-11-17 | Clemson | Duke | REG (Conf) | W 35-6 | ||
| 10 | 10 | 12 | 2018-11-24 | Clemson | South Carolina | REG (Non-Conf) | W 56-35 | ||
| 11 | 11 | 13 | 2018-12-01 | Clemson | N | Pitt | Conf Championship | W 42-10 | |
| 12 | 12 | 14 | 2018-12-29 | Clemson | N | Notre Dame | CFB Semifinal | W 30-3 | Cotton Bowl |
| 13 | 13 | 15 | 2019-01-07 | Clemson | N | Alabama | CFB Championship | W 44-16 | College Football Playoff National Championship |
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 14 | 14 | 1 | 2019-08-29 | Clemson | Georgia Tech | REG (Conf) | W 52-14 | ||
| 15 | 15 | 2 | 2019-09-07 | Clemson | Texas A&M | REG (Non-Conf) | W 24-10 | ||
| 16 | 16 | 3 | 2019-09-14 | Clemson | @ | Syracuse | REG (Conf) | W 41-6 | |
| 17 | 17 | 4 | 2019-09-21 | Clemson | Charlotte | REG (Non-Conf) | W 52-10 | ||
| 18 | 18 | 5 | 2019-09-28 | Clemson | @ | North Carolina | REG (Conf) | W 21-20 | |
| 19 | 19 | 6 | 2019-10-12 | Clemson | Florida State | REG (Conf) | W 45-14 | ||
| 20 | 20 | 7 | 2019-10-19 | Clemson | @ | Louisville | REG (Conf) | W 45-10 | |
| 21 | 21 | 8 | 2019-10-26 | Clemson | Boston College | REG (Conf) | W 59-7 | ||
| 22 | 22 | 9 | 2019-11-02 | Clemson | Wofford | REG (Non-Conf) | W 59-14 | ||
| 23 | 23 | 10 | 2019-11-09 | Clemson | @ | North Carolina State | REG (Conf) | W 55-10 | |
| 24 | 24 | 11 | 2019-11-16 | Clemson | Wake Forest | REG (Conf) | W 52-3 | ||
| 25 | 25 | 12 | 2019-11-30 | Clemson | @ | South Carolina | REG (Non-Conf) | W 38-3 | |
| 26 | 26 | 13 | 2019-12-07 | Clemson | N | Virginia | Conf Championship | W 62-17 | |
| 27 | 27 | 14 | 2019-12-28 | Clemson | N | Ohio State | CFB Semifinal | W 29-23 | Fiesta Bowl |
| 28 | 28 | 15 | 2020-01-13 | Clemson | N | LSU | CFB Championship | L 25-42 | College Football Playoff National Championship |
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 29 | 29 | 1 | 2020-09-12 | Clemson | @ | Wake Forest | REG (Conf) | W 37-13 | |
| 30 | 30 | 2 | 2020-09-19 | Clemson | Citadel | REG (Non-Conf) | W 49-0 | ||
| 31 | 31 | 3 | 2020-10-03 | Clemson | Virginia | REG (Conf) | W 41-23 | ||
| 32 | 32 | 4 | 2020-10-10 | Clemson | Miami (FL) | REG (Conf) | W 42-17 | ||
| 33 | 33 | 5 | 2020-10-17 | Clemson | @ | Georgia Tech | REG (Conf) | W 73-7 | |
| 34 | 34 | 6 | 2020-10-24 | Clemson | Syracuse | REG (Conf) | W 47-21 | ||
| 35 | 35 | 7 | 2020-10-31 | Clemson | Boston College | REG (Conf) | W 34-28 | ||
| 36 | 36 | 8 | 2020-11-07 | Clemson | @ | Notre Dame | REG (Conf) | L 40-47 (2OT) | |
| 37 | 37 | 9 | 2020-11-28 | Clemson | Pitt | REG (Conf) | W 52-17 | ||
| 38 | 38 | 10 | 2020-12-05 | Clemson | @ | Virginia Tech | REG (Conf) | W 45-10 | |
| 39 | 39 | 11 | 2020-12-19 | Clemson | N | Notre Dame | Conf Championship | W 34-10 | |
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 40 | 40 | 1 | 2021-09-04 | Clemson | N | Georgia | REG (Non-Conf) | L 3-10 | |
| 41 | 41 | 2 | 2021-09-11 | Clemson | South Carolina St. | REG (Non-Conf) | W 49-3 | ||
| 42 | 42 | 3 | 2021-09-18 | Clemson | Georgia Tech | REG (Conf) | W 14-8 | ||
| 43 | 43 | 4 | 2021-09-25 | Clemson | @ | North Carolina State | REG (Conf) | L 21-27 | |
| 44 | 44 | 5 | 2021-10-02 | Clemson | Boston College | REG (Conf) | W 19-13 | ||
| 45 | 45 | 6 | 2021-10-15 | Clemson | @ | Syracuse | REG (Conf) | W 17-14 | |
| 46 | 46 | 7 | 2021-10-23 | Clemson | @ | Pitt | REG (Conf) | L 17-27 | |
| 41-5 |
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