| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | |
|---|---|---|---|---|---|---|---|---|
| 1 | 13 | 6 | 2021-10-15 | Clemson | @ | Syracuse | REG (Conf) | W 17-14 |
| 2 | 14 | 7 | 2021-10-23 | Clemson | @ | Pitt | REG (Conf) | L 17-27 |
| 3 | 15 | 8 | 2021-10-30 | Clemson | Florida State | REG (Conf) | W 30-20 | |
| 4 | 16 | 9 | 2021-11-06 | Clemson | @ | Louisville | REG (Conf) | W 30-24 |
| 5 | 17 | 10 | 2021-11-13 | Clemson | Connecticut | REG (Non-Conf) | W 44-7 | |
| 6 | 18 | 11 | 2021-11-20 | Clemson | Wake Forest | REG (Conf) | W 48-27 | |
| 7 | 19 | 12 | 2021-11-27 | Clemson | @ | South Carolina | REG (Non-Conf) | W 30-0 |
| 6-1 |
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