Output includes regular season games from 2000 to 2024 and bowl games from 2002 to 2024.
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | 4 | 2018-09-22 | Houston | Texas Southern | REG (Non-Conf) | W 70-14 | ||
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 2 | 2 | 1 | 2019-09-01 | Houston | @ | Oklahoma | REG (Non-Conf) | L 31-49 | |
| 3 | 3 | 2 | 2019-09-07 | Houston | Prairie View | REG (Non-Conf) | W 37-17 | ||
| 4 | 4 | 5 | 2019-09-28 | Houston | @ | North Texas | REG (Non-Conf) | W 46-25 | |
| 5 | 5 | 6 | 2019-10-12 | Houston | Cincinnati | REG (Conf) | L 23-38 | ||
| 6 | 6 | 7 | 2019-10-19 | Houston | @ | Connecticut | REG (Conf) | W 24-17 | |
| 7 | 7 | 8 | 2019-10-24 | Houston | SMU | REG (Conf) | L 31-34 | ||
| 8 | 8 | 9 | 2019-11-02 | Houston | @ | UCF | REG (Conf) | L 29-44 | |
| 9 | 9 | 10 | 2019-11-16 | Houston | Memphis | REG (Conf) | L 27-45 | ||
| 10 | 10 | 12 | 2019-11-30 | Houston | Navy | REG (Conf) | L 41-56 | ||
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 11 | 11 | 1 | 2020-10-08 | Houston | Tulane | REG (Conf) | W 49-31 | ||
| 12 | 12 | 3 | 2020-10-24 | Houston | @ | Navy | REG (Conf) | W 37-21 | |
| 13 | 13 | 4 | 2020-10-31 | Houston | UCF | REG (Conf) | L 21-44 | ||
| 14 | 14 | 5 | 2020-11-07 | Houston | @ | Cincinnati | REG (Conf) | L 10-38 | |
| 15 | 15 | 7 | 2020-12-12 | Houston | @ | Memphis | REG (Conf) | L 27-30 | |
| 16 | 16 | 8 | 2020-12-24 | Houston | N | Hawaii | Bowl | L 14-28 | New Mexico Bowl |
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 17 | 17 | 1 | 2021-09-04 | Houston | N | Texas Tech | REG (Non-Conf) | L 21-38 | |
| 18 | 18 | 2 | 2021-09-11 | Houston | @ | Rice | REG (Non-Conf) | W 44-7 | |
| 19 | 19 | 3 | 2021-09-18 | Houston | Grambling | REG (Non-Conf) | W 45-0 | ||
| 20 | 20 | 4 | 2021-09-25 | Houston | Navy | REG (Conf) | W 28-20 | ||
| 21 | 21 | 5 | 2021-10-01 | Houston | @ | Tulsa | REG (Conf) | W 45-10 | |
| 22 | 22 | 6 | 2021-10-07 | Houston | @ | Tulane | REG (Conf) | W 40-22 | |
| 23 | 23 | 7 | 2021-10-23 | Houston | East Carolina | REG (Conf) | W 31-24 | ||
| 24 | 24 | 8 | 2021-10-30 | Houston | SMU | REG (Conf) | W 44-37 | ||
| 25 | 25 | 9 | 2021-11-06 | Houston | @ | South Florida | REG (Conf) | W 54-42 | |
| 26 | 26 | 10 | 2021-11-13 | Houston | @ | Temple | REG (Conf) | W 37-8 | |
| 27 | 27 | 11 | 2021-11-19 | Houston | Memphis | REG (Conf) | W 31-13 | ||
| 28 | 28 | 13 | 2021-12-04 | Houston | @ | Cincinnati | Conf Championship | L 20-35 | |
| 29 | 29 | 14 | 2021-12-28 | Houston | N | Auburn | Bowl | W 17-13 | Birmingham Bowl |
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 30 | 30 | 1 | 2022-09-03 | Houston | @ | UTSA | REG (Non-Conf) | W 37-35 (3OT) | |
| 31 | 31 | 2 | 2022-09-10 | Houston | @ | Texas Tech | REG (Non-Conf) | L 30-33 (2OT) | |
| 32 | 32 | 3 | 2022-09-17 | Houston | Kansas | REG (Non-Conf) | L 30-48 | ||
| 33 | 33 | 4 | 2022-09-24 | Houston | Rice | REG (Non-Conf) | W 34-27 | ||
| 34 | 34 | 5 | 2022-09-30 | Houston | Tulane | REG (Conf) | L 24-27 (OT) | ||
| 35 | 35 | 6 | 2022-10-07 | Houston | @ | Memphis | REG (Conf) | W 33-32 | |
| 36 | 36 | 7 | 2022-10-22 | Houston | @ | Navy | REG (Conf) | W 38-20 | |
| 37 | 37 | 8 | 2022-10-29 | Houston | South Florida | REG (Conf) | W 42-27 | ||
| 38 | 38 | 9 | 2022-11-05 | Houston | @ | SMU | REG (Conf) | L 63-77 | |
| 39 | 39 | 10 | 2022-11-12 | Houston | Temple | REG (Conf) | W 43-36 | ||
| 40 | 40 | 11 | 2022-11-19 | Houston | @ | East Carolina | REG (Conf) | W 42-3 | |
| 41 | 41 | 12 | 2022-11-26 | Houston | Tulsa | REG (Conf) | L 30-37 | ||
| 42 | 42 | 13 | 2022-12-23 | Houston | N | Louisiana | Bowl | W 23-16 | Independence Bowl |
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
| 43 | 43 | 1 | 2023-09-02 | Houston | UTSA | REG (Non-Conf) | W 17-14 | ||
| 44 | 44 | 2 | 2023-09-09 | Houston | @ | Rice | REG (Non-Conf) | L 41-43 (2OT) | |
| 45 | 45 | 3 | 2023-09-16 | Houston | Texas Christian | REG (Conf) | L 13-36 | ||
| 46 | 46 | 4 | 2023-09-23 | Houston | Sam Houston | REG (Non-Conf) | W 38-7 | ||
| 47 | 47 | 5 | 2023-09-30 | Houston | @ | Texas Tech | REG (Conf) | L 28-49 | |
| 48 | 48 | 6 | 2023-10-12 | Houston | West Virginia | REG (Conf) | W 41-39 | ||
| 49 | 49 | 7 | 2023-10-21 | Houston | Texas | REG (Conf) | L 24-31 | ||
| 50 | 50 | 8 | 2023-10-28 | Houston | @ | Kansas State | REG (Conf) | L 0-41 | |
| 51 | 51 | 9 | 2023-11-04 | Houston | @ | Baylor | REG (Conf) | W 25-24 (OT) | |
| 52 | 52 | 10 | 2023-11-11 | Houston | Cincinnati | REG (Conf) | L 14-24 | ||
| 53 | 53 | 12 | 2023-11-25 | Houston | @ | UCF | REG (Conf) | L 13-27 | |
| 29-24 |
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