Output includes regular season games from 2000 to 2024 and bowl games from 2002 to 2024.
| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | |
|---|---|---|---|---|---|---|---|---|
| 1 | 1 | 1 | 2021-09-04 | South Alabama | Southern Mississippi | REG (Non-Conf) | W 31-7 | |
| 2 | 2 | 2 | 2021-09-11 | South Alabama | @ | Bowling Green | REG (Non-Conf) | W 22-19 |
| 3 | 3 | 3 | 2021-09-18 | South Alabama | Alcorn St. | REG (Non-Conf) | W 28-21 | |
| 4 | 4 | 4 | 2021-10-02 | South Alabama | Louisiana | REG (Conf) | L 18-20 | |
| 5 | 5 | 5 | 2021-10-09 | South Alabama | @ | Texas State | REG (Conf) | L 31-33 |
| 6 | 6 | 6 | 2021-10-14 | South Alabama | Georgia Southern | REG (Conf) | W 41-14 | |
| 7 | 7 | 7 | 2021-10-23 | South Alabama | @ | Louisiana-Monroe | REG (Conf) | L 31-41 |
| 8 | 8 | 8 | 2021-10-30 | South Alabama | Arkansas State | REG (Conf) | W 31-13 | |
| 9 | 9 | 9 | 2021-11-06 | South Alabama | @ | Troy | REG (Conf) | L 24-31 |
| 10 | 10 | 10 | 2021-11-13 | South Alabama | @ | Appalachian State | REG (Conf) | L 7-31 |
| 11 | 11 | 11 | 2021-11-20 | South Alabama | @ | Tennessee | REG (Non-Conf) | L 14-60 |
| 12 | 12 | 12 | 2021-11-26 | South Alabama | Coastal Carolina | REG (Conf) | L 21-27 | |
| 5-7 |
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