| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 6 | 1 | 2022-09-03 | Notre Dame | @ | Ohio State | REG (Non-Conf) | L 10-21 | |
| 2 | 7 | 2 | 2022-09-10 | Notre Dame | Marshall | REG (Non-Conf) | L 21-26 | ||
| 3 | 8 | 3 | 2022-09-17 | Notre Dame | California | REG (Non-Conf) | W 24-17 | ||
| 4 | 9 | 4 | 2022-09-24 | Notre Dame | @ | North Carolina | REG (Non-Conf) | W 45-32 | |
| 5 | 10 | 5 | 2022-10-08 | Notre Dame | N | BYU | REG (Non-Conf) | W 28-20 | |
| 6 | 11 | 6 | 2022-10-15 | Notre Dame | Stanford | REG (Non-Conf) | L 14-16 | ||
| 7 | 12 | 7 | 2022-10-22 | Notre Dame | Nevada-Las Vegas | REG (Non-Conf) | W 44-21 | ||
| 8 | 13 | 8 | 2022-10-29 | Notre Dame | @ | Syracuse | REG (Non-Conf) | W 41-24 | |
| 9 | 14 | 9 | 2022-11-05 | Notre Dame | Clemson | REG (Non-Conf) | W 35-14 | ||
| 10 | 15 | 10 | 2022-11-12 | Notre Dame | N | Navy | REG (Non-Conf) | W 35-32 | |
| 11 | 16 | 11 | 2022-11-19 | Notre Dame | Boston College | REG (Non-Conf) | W 44-0 | ||
| 12 | 17 | 12 | 2022-11-26 | Notre Dame | @ | USC | REG (Non-Conf) | L 27-38 | |
| 13 | 18 | 13 | 2022-12-30 | Notre Dame | N | South Carolina | Bowl | W 45-38 | Gator Bowl |
| 9-4 |
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