| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 5 | 1 | 2018-09-01 | Clemson | Furman | REG (Non-Conf) | W 48-7 | ||
| 2 | 6 | 3 | 2018-09-15 | Clemson | Georgia Southern | REG (Non-Conf) | W 38-7 | ||
| 3 | 7 | 4 | 2018-09-22 | Clemson | @ | Georgia Tech | REG (Conf) | W 49-21 | |
| 4 | 8 | 6 | 2018-10-06 | Clemson | @ | Wake Forest | REG (Conf) | W 63-3 | |
| 5 | 9 | 7 | 2018-10-20 | Clemson | North Carolina State | REG (Conf) | W 41-7 | ||
| 6 | 10 | 8 | 2018-10-27 | Clemson | @ | Florida State | REG (Conf) | W 59-10 | |
| 7 | 11 | 9 | 2018-11-03 | Clemson | Louisville | REG (Conf) | W 77-16 | ||
| 8 | 12 | 10 | 2018-11-10 | Clemson | @ | Boston College | REG (Conf) | W 27-7 | |
| 9 | 13 | 11 | 2018-11-17 | Clemson | Duke | REG (Conf) | W 35-6 | ||
| 10 | 14 | 13 | 2018-12-01 | Clemson | N | Pitt | Conf Championship | W 42-10 | |
| 11 | 15 | 14 | 2018-12-29 | Clemson | N | Notre Dame | CFB Semifinal | W 30-3 | Cotton Bowl |
| 12 | 16 | 15 | 2019-01-07 | Clemson | N | Alabama | CFB Championship | W 44-16 | College Football Playoff National Championship |
| 12-0 |
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